| ncRNA name | PAUPAR |
| ncRNA Category | lncRNA |
| ID | 103157000 |
| Ensembl | ENSG00000281880 |
| Synonyms | |
| Disease name | uveal melanoma (UM) |
| Species | Homo sapiens |
| Tissues/Cell_line | human UM cell lines MUM2B, OCM1, OM431; human embryonic kidney cell line HEK293T; human RPE cell line ARPE-19 |
| Methods | qRT-PCR, xenograft, siRNA transfection, Western blot, Chromatin immunoprecipitation |
| Expression pattern | down-regulated |
| Functional description | The ectopic expression of PAUPAR in UM cells revealed that PAUPAR acts as a necessary UM suppressor and induces the silencing of HES1 expression, which significantly reduces tumour metastasis. |
| PubMed ID | 27214741 |
| Year | 2016 |
| Title | PAUPAR lncRNA suppresses tumourigenesis by H3K4 demethylation in uveal melanoma. |
| Drug-related ncRNA | NO |
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